摘要: |
黄黄连是我国传统中药材,近些年研究发现,黄连花薹与黄连有相似的化学活性物质,均含有小檗碱、黄连碱、巴马汀、药根碱等多种生物碱类、黄酮类、苯丙素类以及有机酸类成分,具有降血脂、降血糖、抗氧化、抗菌等功效作用,且黄连花薹在国内部分地区有食用历史。作为黄连的副产物,主要应用于黄连花薹茶饮。目前黄连花薹的急性毒性、亚慢毒性、遗传毒性等方面的毒理学研究,未发现其毒性作用,有较好的安全性。本文对近些年黄连花薹的化学成分、药理作用、毒理学研究以及应用情况进行简单的综述,为进一步综合开发和应用黄连花薹作为保健食品或食品的提供思路。 |
关键词: 黄连花薹,化学成分,药理作用,毒理 |
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基金项目:国家重点研发计划项目(2023YFF1104002-01) |
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Recearch progress on chemical composition,pharmacological effects and toxicolgy of Coptis chinensis Inflorescence |
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Abstract: |
Abstract: Coptis chinensis Franch. is a traditional Chinese medicinal material in my country. In recent years, studies have found that Coptis chinensis Franch. and Coptis chinensis inflorescence have similar chemical active substances, including berberine, coptisine, palmatine, jatrorrhizine and the other alkaloids, flavonoids, phenylpropanoids and organic acid ingredients. It has effects on lowering blood fat, lowing blood sugar, antioxidant, antibacterial and so on. Coptis chinensis inflorescence has a history of consumption in some regions of our country. As a by-product of Coptis chinensis, it was mainly produced into Coptis chinensis flower tea. At present, its toxic effects have not been found on the acute toxicity, sub-slow toxicity and genetic toxicity of Coptis chinensis inflorescence with high safety. The review is to briefly summarize chemical composition, pharmacological effect, toxicology and current application of Coptis chinensis inflorescence in recent years, to provide potential candidates for synthetic exploitation and reasonable application of Coptis chinensis inflorescence as healthy products or food. |
Key words: Coptis chinensis inflorescence,Chemical composition,Pharmacological effect,Toxicology |