| 摘要: |
| 石斛防治眼部疾病历史悠久，且疗效显著。近年来石斛方剂及石斛活性成分在防治眼部疾病方面的研究也与日俱增。总结石斛方剂和生物碱、多糖、石斛酚、毛兰素等石斛活性成分对白内障、视网膜疾病、干眼症等常见眼科疾病的改善作用，并分析了石斛活性成分防治眼部疾病的作用机制，探讨了石斛活性成分有望开发为临床防治眼科疾病药物。 |
| 关键词: 石斛方剂 活性成分 白内障 干眼症 |
| DOI：10.14188/j.ajsh.20230918001 |
| 分类号:R932 |
| 基金项目:遵义市科技计划：遵市科合HZ字（2020）69号；贵州省科技支撑计划：黔科合基础-ZK［2022］-596；贵州省科技平台及人才计划：黔科平台人才［2020］-040；贵州省科技支撑计划：黔科合基础-ZK［2023］-575；遵义市科技计划：遵市科合HZ字（2022）245号 |
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| Application of Dendrobium prescriptions and its active ingredients in the treatment of ophthalmic diseases |
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LIU Bo1, HUANG Bo1, GUO Mian2, SHI Jingshan1
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1.Key Laboratory of Basic Pharmacology of Ministry of Education， Zunyi Medical University， Zunyi 560003， Guizhou， China;2.Department of Ophthalmology， Affiliated Hospital of Zunyi Medical University， Zunyi 560003， Guizhou， China
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| Abstract: |
| Dendrobium species have a long history of treatment of eye diseases， and have remarkable curative effects. In recent years， the research of Dendrobium prescriptions and its active ingredients on the prevention and treatment of eye diseases has been increasing day by day. This review focuses on the improvement effect of its prescriptions and active components， such as alkaloids， polysaccharides， Dendrobium phenols and mulanins on common eye diseases such as cataract， retinal diseases， dry eye diseases， and analyzes the mechanism of action of Dendrobium active ingredients in the prevention and treatment of eye diseases. Moreover， this review discusses the prospect of Dendrobium active ingredients in clinical prevention and treatment of eye diseases. |
| Key words: Dendrobium prescription active ingredient cataract xerophthalmia |
