| 摘要: |
| 我国是世界第一大生猪养殖国，猪肉在我国肉类食品组成中占有重要地位，是国人获取动物蛋白的重要来源。猪肉中ω-6多不饱和脂肪酸(polyunsaturated fatty acids, PUFAs)含量高，而ω-3 PUFAs含量少，不利于人类健康。基因工程技术可以对特定DNA片段敲除、插入和替换，在改良猪生产性状方面具有巨大潜力，采用基因工程培育富含ω-3 PUFAs猪具有巨大的市场价值。本文阐述了猪肉ω-3 PUFAs含量少的原因，并就利用基因工程技术培育富含ω-3 PUFAs猪的研究进展进行了分析，以期为提升猪肉ω-3 PUFAs含量的相关研究与实践奠定基础。 |
| 关键词: 猪 猪肉 多不饱和脂肪酸 脂肪酸脱氢酶 基因工程 |
| DOI：10.14188/j.ajsh.2019.03.003 |
| 分类号:S814.8 |
| 基金项目:2018ZX08010-08B)、广东省重点领域研发计划(2018B020203003)和佛山市科技创新项目计划 2017AG100111国家科技重大专项(2009ZX08010-023B，2018ZX08010-08B)、广东省重点领域研发计划(2018B020203003)和佛山市科技创新项目计划(2017AG100111) |
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| Research progress on genetic engineered pigs rich in ω-3 PUFAs |
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WEI Yanyan1,ZHAN Qunmei1,ZHU Xiangxing1,TANG Dongsheng1
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Guangdong Gene Editing Engineering Technology Research Center, Foshan University, Foshan 528000, Guangdong, China
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| Abstract: |
| China is the largest pig farming country in the world. Pork plays an important role in the composition of meat products in China and is an important source of animal protein for Chinene people. The content of ω-6 polyunsaturated fatty acids (PUFA) in pork is high, while the content of ω-3 PUFAs is low, which is not conducive to human health. Genetic engineering technology can knock out, insert and replace specific DNA fragments, and has great potential in improving pig production traits. It is of great market value to breed pigs rich in ω-3 PUFAs by genetic engineering technique. In this paper, the reasons for the low content of ω-3 PUFAs in pork are described, and the research progress of using genetic engineering technique to creat pigs rich in ω-3 PUFAs is reviewed. This paper lays a foundation for the research and practice of improving the content of pork rich in ω-3 PUFAs. |
| Key words: pig pork polyunsaturated fatty acid Fat-1 genetic engineering |
